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Mixed-Mode Debugging Error

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We recently received 64-bit Windows 7 PCs.  Also, we have a new site in our solution that is .Net 4, the others are still .Net 2.  I can no longer debug my .Net code in Visual Studio 2010.

If I try try to start the web app in VS with debugging, I get a "mixed-mode" not allowed error.

  • I cannot convert all sites to .Net 4 at this time
  • My solution platform is ANY CPU with no other options.  I suspect this due to web sites as opposed to VS projects.

There was a time I could start the app in IE and attach to a single site in VS and debug, but since IE 10 loaded, I can no longer even do that, even though I backed out of IE 10. 

I did run the following, based on another post I found, but did not solve the problem:

regsvr32.exe "%ProgramFiles(x86)%\Common Files\Microsoft Shared\VS7Debug\msdbg2.dll"


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